CBD is a natural compound found in the Sativa plant. It has been found to provide a variety of benefits, ranging from reduced anxiety and seizures to nausea and pain relief. Best of all, CBD contains 0.3% THC or less, so it does not produce psychoactive effects or feelings of being “stoned” in people who take it.
Thanks to its non-psychoactive properties and the wealth of health benefits, CBD is becoming an increasingly popular alternative for people who want natural therapies for the conditions that afflict them.
Research on CBD is very promising, and people all over the world are touching it as a safe solution, almost a miracle drug. But are there any disadvantages to taking CBD? Specifically, are there negative side effects?
Generally, research indicates that CBD side effects are minimal and rare. Of course, a caveat to all of this is that most CBD research has been done on animals, not humans, and we have different physiologies. Still, so far the research indicates that CBD tends to be well tolerated by people, even with chronic use or doses as high as 1500 mg/day.
However, if you plan to take CBD, you should be aware of possible side effects and risk factors. We review these below.
What are the side effects of CBD?
While experiencing side effects is rare, the most commonly reported side effects of CBD include
- Fatigue or tiredness
- Diarrhea
- Nausea
- Changes in appetite or weight
- Dry Mouth
- Low blood pressure
Whether or not you experience side effects may depend on the amount of CBD you take, your age, your weight, any health conditions you may have, any medications you may be taking, and environmental factors.
It is important to note that these side effects are rare and if you experience them once, you may not necessarily experience them every time you take CBD. More importantly, CBD does not appear to cause any serious negative side effects, such as an impact on blood pressure, body temperature, or heart rate. This is a big reason why CBD is gaining favor with scientific researchers and health professionals.

Who should avoid CBD?
CBD generally seems safe. However, doctors warn against certain groups of people using the drug. Currently, this list of potentially at risk includes pregnant and nursing women, people who are taking other drugs, and children.
Pregnant and Nursing Women
Pregnant and lactating women are used to seeing safety warnings on products. Researchers tend to avoid the use of pregnant and breastfeeding women in clinical research in order to avoid adverse outcomes that could harm the mother or her baby. To date, not enough CBD research has been done to allow medical professionals to provide recommendations on the use of CBD among this demographic.
People who are taking other medications
Often, when side effects have been reported with CBD, it has been among people who are taking other medications. The side effects are typically due to the interaction between CBD and the other drugs, rather than being caused by the CBD itself. For example, CBD has been shown to increase the liver concentration of some drugs, which could lead to liver damage.
If you are taking another medication, be sure to talk to your doctor first before taking CBD. They can best advise you on the safety of mixing CBD with your medication and provide recommendations on the appropriate dosage or types of CBD products to use.
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